At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description:
We are seeking a highly motivated Senior Associate Scientist to join the Research Oncology group and contribute to the discovery and development of novel oncology therapies. The successful candidate will have hands-on expertise in immunology, mammalian cell culture, primary immune cell biology, flow cytometry, target validation, and cell engineering. The candidate will demonstrate scientific rigor, strong experimental execution, and the ability to independently generate, interpret, and communicate high-quality data. The successful candidate will be proficient in developing and executing in vitro assays to support target validation, mechanism-of-action studies, lead discovery, and candidate characterization. Experience with primary immune cells, reporter assays, cytotoxicity assays, and engineered cellular systems is highly desirable. Exposure to in vivo pharmacology studies, including preclinical mouse models, tissue processing, and translational assessment, is preferred. Working within multidisciplinary teams, this individual will generate high-quality data, solve complex scientific challenges, and help advance innovative therapies from concept to candidate selection.
Key Responsibilities:
Develop cell-based assays using primary and engineered mammalian cells to evaluate and characterize drug candidates.
Design and execute experiments to screen and characterize preclinical and clinical-stage candidates within our engager pipeline.
Perform mammalian cell culture, gene engineering, and stable cell line generation to support discovery and mechanistic studies.
Isolate and characterize primary immune cells using flow cytometry and other cellular analysis techniques.
Conduct a range of cell-based functional assays, including reporter, proliferation, and cytotoxicity assays.
Collaborate with cross-functional teams across diverse therapeutic areas, with a primary focus on immuno-oncology/engagers.
Apply innovative experimental approaches, learn new technologies, and contribute to multiple projects in a fast-paced research environment. Analyze and interpret experimental data and communicate findings through team discussions and cross-functional presentations.
Contribute to the design, execution, and interpretation of in vivo studies; hands-on experience with preclinical mouse models, dosing, tissue collection, and pharmacology studies is highly desirable.
Basic Qualifications:
5+ Years with BSOR3+ Years with MSPreferred Qualifications Bachelor's degree in Immunology, Biology, Biochemistry, Pharmacology, Molecular Biology, Oncology, Pharmaceutical Sciences, or a related scientific discipline with 5+ years of relevant industry experience, ORMaster's degree in Immunology, Biology, Biochemistry, Pharmacology, Molecular Biology, Oncology, Pharmaceutical Sciences, or a related scientific discipline with 3+ years of relevant industry experience. Industry experience supporting drug discovery, translational research, assay development, screening sciences, pharmacology, bioanalysis, or a related scientific discipline. Knowledge of immunology, protein biology, and mammalian cell culture techniques; hands-on bench research experience preferred Ability to multitask experiments and data analysis across diverse projects Experience working independently as well as within a collaborative team environment Ability to communicate effectively within a large team Excellent adaptability and flexibility, with great attention to detail and outstanding organizational skills A background in in-vitro T cell characterization (functional and antigen-binding assays) is a plus Experience with cell-based assays, immunoassays (flow cytometry or plate reader-based) and basic molecular biology techniques is also a plus High-throughput screening experience and familiarity with liquid handlers are beneficial Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams. Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose. Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem. The salary range for this position is: $126,820.00 - $164,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.For additional benefits information, visit: * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACTYOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACTGilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.
Summary
Location: United States - California - Foster City
Type: Full time
