We’re Hiring: Scientist I – Discovery Biology | T-Cell Engineering Are you a hands-on Wet Lab Scientist passionate about immunology, T-cell engineering, and therapeutic discovery? Join a high-priority discovery campaign focused on screening and validating novel binders for next-generation T-cell-based therapies.
Position Details
Job Title: Scientist I – Discovery Biology.
Location: San Diego, CA (Onsite).
Pay Rate: $43–$48/hour on W2.
Duration: 8 Months.
Key Responsibilities:
Perform primary human T-cell isolation, culture, expansion, and non-viral engineering using electroporation or nucleofection.
Execute multi-color flow cytometry (FACS) and analyze results using FlowJo.
Conduct functional assays, including T-cell activation, cytotoxicity, cytokine profiling, and proliferation assays.
Work with primary T cells, Jurkat cell lines, and candidate binders such as scFvs and VHHs.
Maintain accurate experimental records in an Electronic Lab Notebook (ELN).Collaborate with cross-functional teams and present data-driven updates during campaign meetings.
Required Qualifications:
Bachelor’s or Master’s degree in Immunology, Molecular Biology, Bioengineering, or a related life science field.2+ years of hands-on wet lab experience, preferably in an industry setting.
Strong expertise in flow cytometry acquisition and data analysis.
Experience with aseptic cell culture and primary T-cell isolation from PBMCs.
Knowledge of functional immunology assays and cell-based screening techniques.
Preferred Skills:- Non-viral transfection experience, including mRNA or transposon-based systems.
- Experience with IncuCyte, LDH, ELISA, MSD, Luminex, or CFSE-based assays.
- Familiarity with liquid-handling robotics and high-throughput screening.
- Interested in contributing to innovative therapeutic discovery? Let’s connect!
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