Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon's discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets. Position We are seeking an enthusiastic and highly motivated Senior Scientist I to join our Neuroscience research team. In this role, you will be a key contributor to our efforts to identify and validate novel therapeutic targets for Parkinson's disease. You will develop and apply complex cellular models and biochemical and cell-based assays to advance target validation and deepen our understanding of disease-relevant mechanisms. This is a highly collaborative, laboratory-focused role with the opportunity to work across disciplines and research sites, partnering with cellular and molecular biologists, in vivo pharmacologists, medicinal chemists, and other scientific colleagues to advance our neuroscience research programs.
About You:
You are a collaborative and rigorous scientist who enjoys solving complex biological questions at the bench. You bring deep expertise in cellular and biochemical approaches and are comfortable independently designing, executing, and interpreting experiments while working as part of a multidisciplinary team. You thrive in a fast-paced research environment and enjoy translating scientific questions into well-designed experiments that can inform target validation and mechanism of action. You are an effective communicator and teammate who values scientific rigor, thoughtful collaboration, and the opportunity to support and develop more junior scientists. An interest in Parkinson's disease and neurodegenerative biology, and in applying your expertise to drug discovery, will position you well for success in this role.
What You'll Do:
Lead and support target validation and mechanism-of-action (MOA) assay development activities.
Execute in vitro experiments in cell lines, primary neurons, iPSC-derived neurons, and glia culture.
Build and execute biochemical and cell-based assays to support novel Parkinson's disease target validation.
Collaborate with and support cellular and molecular biologists, in vivo pharmacologists, and medicinal chemists across research sites.
Support the training and guidance of junior research associates and interns, fostering a collaborative and productive research environment. Stay up to date with the latest advancements in Parkinson's disease research by attending relevant conferences and workshops.
Contribute to the preparation of research publications, presentations, and grant proposals, showcasing the team's contributions to the field.
Maintain organized and comprehensive records of experiments, results, and protocols in adherence to company standards and regulatory requirements.
Uphold a culture of safety by strictly following laboratory protocols and promoting best practices in accordance with regulatory guidelines.
Qualifications:
Postdoc Fellowship plus 2 years of relevant experience or Ph.D. plus 5 years of relevant experience, or a Master's degree plus 14 years of relevant experience or a Bachelor's degree plus 16 years of relevant experience in Neuroscience, Cell Biology, Biochemistry, Pharmacology, or a related scientific discipline. Highly proficient in cell culture techniques, including primary neurons and glia. Proficiency with standard cell biology, biochemistry, enzymology, and neuroscience techniques, including confocal microscopy/high-content imaging, protein detection and quantification (such as ELISA and MSD), and enzyme kinetic assays. Extensive bench research experience and enjoyment of a laboratory-focused role in a fast-paced, multidisciplinary team. Ability to design, execute, and interpret experiments independently. Excellent written and verbal communication skills. Strong interpersonal and teamwork skills paired with a strong work ethic. Experience in iPSC-derived cells and/or complex co-culture model systems is preferred. At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:401k plan with company matching Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)Mental health and wellness benefits Weeklong summer and winter holiday shutdowns Generous paid time off and holiday policies Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies Enhanced parental leave benefit Daily subsidized lunch program when on-site The expected salary range for this role is $143,000 to $173,250 depending on skills, competency, and the market demand for your expertise. Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment. We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.
