ASSOCIATE DIRECTOR, BIOSTATISTICS DCRI

Work Arrangement: Remote-first, with in-person collaboration in Durham expected a couple of times per month. Duke remote workers must reside in an eligible state. The Duke Clinical Research Institute (DCRI), part of the Duke University School Of Medicine, is the largest full-service, mission-driven academic clinical research organization. We combine insights from practicing physicians in a world-class health system with unmatched data science expertise and an end-to-end operations infrastructure. Our model ensures studies and trials of all sizes run effectively, achieve the best outcomes, and transform health care for our patients and people everywhere.

The Opportunity: Biostatistics at the Duke Clinical Research Institute is entering an exciting new chapter. As DCRI expands its capabilities in biostatistics, biomedical informatics, and data science, this role offers a unique opportunity to help shape the future scope of clinical research—moving beyond traditional Phase II/III trial support to advance innovative, pragmatic research and AI-enabled discovery. The Associate Director will play a central leadership role in this transformation, helping build a forward-looking biostatistics enterprise known for scientific rigor, methodological innovation, and meaningful impact on human health. You will lead a team of talented biostatisticians while serving as a strategic leader who helps define what DCRI's biostatistics enterprise can become. We are looking for someone with deep statistical expertise and the leadership instincts to cultivate team science, grow new capabilities, and drive AI integration into research and operations. In two to three years, this person will have built a team recognized not just for study execution, but for innovation and thought leadership — a team that embodies Duke's values of collaboration, inclusion, and scientific rigor, and that sponsors seek out as a strategic partner rather than a technical resource. This staff role closely collaborates with and supports faculty; it is not intended as a path to a faculty position.

Position Summary: The Associate Director leads the assigned Biostatistics team across operations, performance management, quality, resource planning, and financial performance — with an explicit mandate to advance DCRI's strategy and transformation agenda. This role is a driver of strategic growth in innovative and pragmatic research, a champion of AI and data science integration, and a cultivator of the team science culture that defines Duke's approach to clinical research.

Education/Experience: Position requires a minimum of a bachelor's degree, nine years of relevant experience to include 4 years in leadership roles OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

Knowledge, Skills and Abilities: Excellent interpersonal, communication, collaborative, and presentation skills. Familiarity with a range of statistical software with fluency in a core language such as SAS and R and operating in experience developing and maintaining reproducible code using version control tools such as Subversion or Git. Strong statistical knowledge and analytical skills. Experience with CDISC standards, safety data, dynamic randomization schemes, platform trials, Data Monitoring Committees and data sharing repositories. Excellent organizational skills demonstrated ability to lead in a team environment, and an ability to supervise and delegate tasks. Excellent working knowledge of clinical, operational, statistical and data operations issues as they pertain to the operations and analyses of clinical trials. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of our community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.