Analytical ChemistIRI believes in commitment, integrity and strategic workforce solutions. Integrated Resources, Inc., is led by a seasoned team with combined decades in the industry. We deliver strategic workforce solutions that help you manage your talent and business more efficiently and effectively. Since launching in 1996, IRI has attracted, assembled and retained key employees who are experts in their fields. This has helped us expand into new sectors and steadily grow. We've stayed true to our focus of finding qualified and experienced professionals in our specialty areas. Our partner-employers know that they can rely on us to find the right match between their needs and the abilities of our top-tier candidates. By continually exceeding their expectations, we have built successful ongoing partnerships that help us stay true to our commitments of performance and integrity. Our team works hard to deliver a tailored approach for each and every client, critical in matching the right employers with the right candidates. We forge partnerships that are meant for the long term and align skills and cultures. At IRI, we know that our success is directly tied to our clients' success.
Job Description:
A position is available for a highly skilled analytical chemist or engineer to join in Pharmacokinetics Dynamics and Metabolism New Biological Entities (PDM-NBE) ADME group with deep expertise in antibody ADME and inter-molecular binding. The lab based role entails training on the state-of-the-art technology for intermolecular interactions and quantification of binding affinity of Biotherapeutics drug to specific proteins in human biological matrices with unwanted immunogenicity. This position requires strong analytical expertise, with background in engineering, protein biochemistry, immunology or PK as a plus. The candidate will participate in all phases of laboratory operations including training on the technology, design of reagents, design of binding experiments, the development of sample preparation, assay execution, instrument maintenance, data analysis, summarization and reporting. We are looking for a scientist passionate about learning and able to quickly apply new skills to the project needs.
Responsibilities:
Design of protein reagents to be used in binding studies. Run binding assays under minimal supervision; initiative in method development is expected. Independent daily operation, calibration, maintenance, and troubleshooting the binding instrument. Analysis of binding data and derive binding affinity using relevant software. Work with modeller to build computational immunogenicity model. Handling of biological samples, specifically human and preclinical serum and tissues. Summarize work and write reports.
Qualifications:
BS/MS level education in Analytical Sciences, Biochemistry, Chemistry, Pharmacology or closely related fields required; advanced degree may be a plus. Industry experience in biopharma preferred. Attention to detail is critical, and be able to handle very delicate and complicated instrument to produce reproducible data. Strong analytical and biochemistry background is required. Good understanding of concepts of binding affinities is a plus. Fast learner and be able to master running/maintaining the instrument after a short period of training. Strong initiative for problem solving at a technical and intellectual level. Excellent communication skills, both written and oral. Works well both independently and as part of a team. Collaborative skills and effective partnering skills in a matrix-environment. Strong data organization and analysis skills.
Additional Information: Thanks. Regards. Ricky.
