Scientist, In Vivo CAR-T Therapy

Scientist – In Vivo CAR-T Therapy Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide. Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma. The Scientist – In Vivo CAR-T Therapy will have the following duties: Design, plan, and execute experimental studies to advance cell and gene therapy platforms and pipeline programs, with a focus on in vivo CAR T development from early discovery through preclinical development. Conduct and analyze in vitro and in vivo studies to evaluate product potency, efficacy, and safety. Develop, optimize, validate, and troubleshoot experimental assays and laboratory methods, including cell line engineering, cell-based functional and cytotoxicity assays, ELISA and PCR-based assays, high-throughput binder screening, and viral vector packaging and titration. Analyze, interpret, and summarize complex scientific data generated from experimental studies and maintain accurate, complete, and well-organized experimental records and documentation. Prepare clear, detailed, and high-quality technical reports, summaries, and presentations to communicate research findings, experimental results, and scientific conclusions. Collaborate closely with internal research and early development teams in a cross-functional environment to support translation of novel scientific concepts into therapeutic candidates and advancement of cell and gene therapy research programs.

To Apply: E-mail CV to: Attn. K Washington: talent.acquisition@legendbiotech.com.Pay Range (Base Pay): $119,692 —$119,692 USDOther Types of Pay: Performance-based bonus and/or equity is available to employees in eligible roles. Benefits and Paid Time Off: Medical, dental, and vision insurance as well as a 401(k) retirement plan with a company match that vests fully on day one. We offer eight (8) weeks of paid parental leave after just three (3) months of employment, and a paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays. Additional voluntary benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide voluntary commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs; demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work.