Postdoctoral Fellow (m/f/d) - Five-Year ERC Advanced Grant

Postdoctoral Fellow (m/f/d) – Five-Year ERC Advanced Grant Institute of Transfusion Medicine The Project ERC Advanced Grant PROTECT | Project BYPASS Engineering Next-Generation Blood Products The Institute of Transfusion Medicine at University Medicine Greifswald is recruiting a full-time postdoctoral fellow for the BYPASS project within the ERC Advanced Grant PROTECT. We are looking for an independent scientist who wants to develop new biotechnology-based strategies for next-generation blood products while building a distinct scientific profile. The position is designed for the full five-year duration of the ERC Advanced Grant. The initial appointment is for one year, with continuation for the remaining grant period explicitly intended. The BYPASS Project The central question of BYPASS is: Can the surface structures of blood cells be engineered so that clinically relevant antibody-mediated reactions are avoided without compromising cellular function? To address this question, approaches from protein engineering, enzyme engineering, glycoengineering, synthetic biology and cell biology will be combined and further developed. The project is deliberately open as to which strategy will ultimately succeed. The aim is to create new biotechnology tools and generate mechanistic insight. The long-term goal is to develop blood products that can be used safely and effectively even in patients with complex immunisation. The programme spans engineering and preclinical testing through manufacturing, quality assurance and regulatory development. This is not a predefined work package. The position offers substantial scientific freedom to develop original concepts and to build an independent research profile within BYPASS.