At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission.
We are seeking a highly motivated Scientist I to join the Content Development team. In this role, you will support the development, optimization, characterization, and execution of NULISA-based immunoassays and multiplex proteomic panels across diverse disease areas, from early feasibility through customer sample testing. You will work closely with cross-functional partners including R&D, Manufacturing, Bioinformatics, and related teams to ensure robust assay performance and high-quality deliverables.
The ideal candidate will bring strong hands-on immunoassay execution skills, a solid foundation in data analysis, and the operational discipline that multiplex work demands: managing many reagents and samples at once, keeping complex experiments organized and traceable, and delivering reliable data on tight timelines.
Primary Responsibilities:
Contribute to the design, development, and optimization of multiplex proteomic panels, including Alamar's own NULISAseq panels as well as custom panels for external collaborators, across various disease areas to support biomarker discovery, validation, and translational research.
Manage reagent logistics for panels with up to thousands of components (antibodies, conjugates, recombinant antigens, calibrators, controls), including inventory, lot tracking, aliquoting, storage, and stability; coordinate material supply with Manufacturing and R&D.
Characterize assay performance for each target, including calibration curves, LLOQ, precision, dilution linearity, spike recovery, and parallelism; evaluate reagent lot-to-lot and instrument-to-instrument consistency.
Run sample testing studies, including sample receipt and tracking, plate mapping, and reconciliation of sample manifests, run records, and QC reports.
Analyze and interpret assay data, including data processing, normalization, QC, and statistical evaluation of multi-plate datasets; work with Bioinformatics to summarize results and present findings to internal teams and external collaborators.
Troubleshoot technical challenges via root-cause analysis across reagent, instrument, sample, and operator factors, and implement corrective strategies.
Develop and maintain critical documentation, including SOPs, reagent preparation records, and assay transfer documents, and provide input to PRDs, to support product development and regulatory compliance.
Collaborate cross-functionally to advance projects and share technical insights with the team.
Requirements:
Ph.D. in Biochemistry, Molecular Biology, or a related discipline; M.S. with 2–5 years of experience will also be considered.
Hands-on experience with immunoassays or multiplex assay platforms (e.g., Luminex, MSD, Olink, Ella, SomaLogic, etc.).
Demonstrated experience running multiplex or high-throughput studies involving large numbers of reagents and samples, with strong organizational skills and meticulous record keeping (e.g., reagent inventories, lot tracking, ELN).
Working knowledge of assay development and validation parameters (e.g., LLOQ, precision, linearity, spike recovery, parallelism).
Proficiency in Excel and/or R or Python for processing and QC of multi-plate datasets.
Experience with antibody conjugation, recombinant protein handling, or lab automation (e.g., liquid handlers) is a plus.
Familiarity with molecular biology methods (e.g., qPCR, ddPCR, or NGS) is a plus.
Strong problem-solving and analytical skills with attention to detail in experimental execution.
Ability to manage multiple projects and timelines in parallel, work collaboratively, and adapt in a fast-paced environment.
Strong communication skills, including data presentation and technical documentation.
Knowledge of biomarker research or clinical sample testing is desirable.
The base salary range for this full-time position is $120,000 - $140,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process.
Please Note:
We participate in E-Verify to confirm authorization to work in the United States.
Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.
As set forth in Alamar Biosciences’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
