Executive Director of Molecular Pathology Our client is a rapidly growing healthcare diagnostics organization focused on advancing innovative molecular testing and improving clinical decision-making for patients with complex cancers. We are conducting a confidential search for an Executive Director, Molecular Pathology to provide senior clinical and technical leadership across high-complexity molecular testing operations. This is a hands-on leadership opportunity for a physician with strong molecular pathology expertise who can combine clinical interpretation, laboratory oversight, regulatory knowledge, quality leadership, and scientific collaboration within a fast-moving organization. The Executive Director will work closely with senior laboratory leadership to provide clinical and technical oversight of high-complexity molecular testing. This position will have direct responsibility for clinical result review, interpretation, physician consultation, and technical decision-making, while sharing accountability for CLIA/CAP compliance, quality assurance, and laboratory personnel oversight. The role is based in the Chicago area and requires regular on-site presence within a CLIA-certified laboratory to fulfill technical oversight, sign-out, and regulatory responsibilities. Provide clinical and technical oversight of high-complexity molecular testing in accordance with CLIA and CAP requirements. Review, interpret, and sign out molecular diagnostic reports. Correlate molecular findings with clinical, radiographic, and histopathologic context for primary and metastatic cancers. Apply current disease classifications, clinical guidelines, and relevant evidence to support accurate and clinically meaningful result interpretation. Serve as a direct clinical resource for ordering physicians and pathologists regarding test selection, specimen requirements, and complex or discordant molecular findings. Support method validation, verification, and ongoing performance monitoring for laboratory-developed tests (LDTs), including sensitivity, specificity, and limit-of-detection studies. Oversee quality assurance and quality control programs, including proficiency testing, competency assessment, corrective actions, and CAPA processes. Assist in supervising, training, and mentoring laboratory personnel. Review and approve standard operating procedures (SOPs).Support regulatory inspections and provide technical leadership when senior laboratory leadership is unavailable. Contribute clinical and scientific expertise to research and development initiatives, including new assay development and expansion of the molecular testing menu. Collaborate closely with clinical, laboratory, scientific, operational, and commercial teams. Help support the continued growth and evolution of the laboratory in a dynamic, entrepreneurial environment. M.D. or D.O. with training in pathology, molecular genetic pathology, neuropathology, or a closely related discipline. Meets applicable qualification requirements for laboratory director/assistant director oversight of high-complexity testing under CLIA.Current, unrestricted medical license. Board certification or board eligibility in Molecular Pathology. Additional expertise in Clinical Pathology, Anatomic Pathology, or Neuropathology is strongly preferred. Demonstrated experience with molecular oncology testing, next-generation sequencing (NGS), and clinical genomic report interpretation. Working knowledge of CLIA and CAP requirements for high-complexity clinical laboratories. Strong written and verbal communication skills with the ability to translate complex molecular findings for physicians and internal teams.
