Flow Cytometry Scientist

Job Description: Our large pharmaceutical client in Spring House, PA is seeking a passionate and talented scientist to join the Clinical Cytometry group within Biomarker Development & Operations. This role will support Oncology clinical programs by delivering fit-for-purpose flow cytometry biomarker assays and high-quality clinical data in a highly collaborative clinical research environment. The successful candidate will be lab-based and should have experience with flow cytometry, primary cell handling, and cell-based assays. The role will focus on designing and executing robust ex vivo flow cytometric assays with immunophenotyping and functional readouts. Hands-on experience with clinical flow cytometry assay development, optimization, analytical validation and clinical sample analysis is highly valued.

Primary responsibilities: Execute multi-parameter clinical flow cytometry biomarker assays end-to-end including assay development, optimization, fit-for-purpose validation, on-time assay deployment for clinical sample testing, and downstream analysis Design, develop, and perform robust ex vivo and in vitro cell-based assays that incorporate functional readouts, including activation, proliferation, cytokine production, and cytotoxicity Handle and isolate primary human cells from blood and cryopreserved specimens for characterization and functional assessment Record experimental data and results accurately and well-organized following SOPs and internal document requirements including writing validation reports Demonstrate the ability to analyze, interpret, and present data in professional 'publication ready' format Demonstrate clear and professional verbal and written communication and effectively present scientific data and concepts Support clinical flow cytometry research projects implemented externally at external service providers/CROs. Monitor data quality resulting from outsourced clinical flow cytometry assays. Perform assay troubleshoot to correct errors, identify root-cause of errors and prevent re-occurrence. Work independently and manage multiple projects simultaneously Demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions