Sr. Manager, Scientific Product Management Plasmids are Addgene's largest and most established product portfolio. They are also the platform from which everything else grows — viral vectors, antibodies, new formats, new markets. The Senior Manager, Scientific Product Management owns day-to-day execution across this portfolio, which includes segmentation, catalog health, roadmap delivery, and launch execution, in close partnership with the Director of Scientific Product Management. Position reports to: Director, Scientific Product Management$130,000 - 155,000 annually + our amazing benefits! This position will work out of our Watertown, Massachusetts Headquarters with an opportunity to work on a hybrid schedule. Our beautiful office space has free, ample parking with a complimentary shuttle from Harvard Square and is on multiple bus lines, with the cost of public transit covered by Addgene for those onsite at least twice a week.
The Role:
This is a role for someone who wants to grow a business — who leads with outcomes, moves with urgency, and knows how to translate scientific insight into commercial results. The right candidate will inherit a portfolio with strong foundations and significant untapped potential, and will be expected to deliver on both in the near term while building the strategic runway for 2028 and beyond.
Portfolio Performance & Analytics:
Track and report on plasmid portfolio performance — including revenue growth, margin optimization, and long-term portfolio health — and deliver on targets set in the Annual Operating Plan (AOP).Set and hit clear performance targets for the portfolio: revenue growth, adoption rates, market penetration, and customer retention across academic, biotech, and pharma segments. Identify performance gaps and recommend pricing, positioning, promotional, or product-mix adjustments to protect and grow commercial outcomes. Product Strategy & Roadmap ExecutionExecute the multi-year plasmid product roadmap, balancing near-term revenue delivery with longer-term innovation bets. Drive the full product lifecycle for the plasmid portfolio — from opportunity identification and concept validation through launch, growth, optimization, and, where appropriate, rationalization. Support the I2L (Idea-to-Launch) pipeline for plasmid-related innovations, including new formats like Transfection-Ready DNA, defining what comes next on that roadmap, and shepherding line extension projects through gate decisions. Apply plasmid segmentation outputs to prioritize where Addgene invests, where it defends, and where it rationalizes — making clear, defensible calls with supporting data. Develop and implement a plasmid intake evaluation framework for large deposits, including accept/decline criteria and cost-benefit analysis, to improve catalog quality and scalability.
Market Insight & Commercial Intelligence:
Run an ongoing Voice of the Customer (VOC) program, translating researcher needs into product priorities and roadmap recommendations. Maintain deep knowledge of the plasmid competitive landscape — who the players are, what they offer, how Addgene is positioned, and where the gaps and white space lie. Monitor market trends, funding shifts, and emerging research applications (e.g., gene therapy, synthetic biology, CRISPR) to anticipate demand and position the portfolio ahead of the curve. Turn market intelligence into concrete recommendations, pricing moves, product concepts, or go-to-market adjustments. Go-to-Market ExecutionExecute annual commercial plans for the plasmid portfolio — launch activities, marketing coordination, channel activation, and partnership initiatives — in partnership with Marketing, Distribution, and Business Development. Own the commercial launch of Transfection-Ready DNA and any subsequent new formats, from go-to-market strategy through post-launch performance monitoring and optimization. Define clear value propositions and messaging for each plasmid segment, ensuring Addgene's positioning is differentiated, credible, and compelling to target customers. Partner with the Distribution Manager to ensure distributor partners are equipped, motivated, and accountable for plasmid sell-through in their markets.2027 Planning & Strategic Roadmap Provide plasmid portfolio analysis and input into the 2027 Operating Plan and 3–5 year commercial roadmap, under the Head of Product Management's direction. Develop business cases and Market Requirements Documents (MRDs) for new product ideas advancing through the I2L process, ensuring each is grounded in customer evidence and commercial viability. Surface partnership opportunities that could accelerate plasmid portfolio growth for the Business Development team to evaluate.
Cross-Functional Leadership:
Lead cross-functional core teams — spanning Operation, R&D, Marketing, Scientific Engagement, Operations, and Digital product— to deliver portfolio objectives on time and to commercial standard. Hold cross-functional partners accountable to shared milestones and commercial outcomes, escalating blockers quickly and decisively. Serve as the internal authority on the plasmid portfolio — the person who knows it best, advocates for it most effectively, and can represent it credibly to any audience. Represent Addgene externally at conferences, partner meetings, and industry events, building market presence and returning with actionable intelligence.
Skills and Competencies:
RequiredBachelor's degree in a life sciences discipline; advanced degree (PhD or master's in molecular biology, biochemistry, genetics, or related field) strongly preferred and carries significant weight.5–7 years of progressive commercial experience in the life sciences sector, including experience in product management, portfolio execution, or a directly adjacent commercial role. Demonstrated track record of owning a product portfolio P&L and delivering revenue growth and margin improvement Deep understanding of discovery researcher needs, workflows, and purchasing behavior in academic and industry settings, with the ability to translate that understanding into commercial strategy. Proven experience leading products through a structured innovation or stage-gate process (I2L, Phase-Gate, or equivalent) from concept through commercial launch. Strong analytical and financial acumen: comfortable building business cases, interpreting performance data, and making data-driven recommendations Demonstrated ability to lead and influence cross-functional teams without direct authority, and to hold peers accountable to shared commercial goals. Excellent communication skills — able to present to executive leadership, engage credibly with scientists, and align commercial teams around a clear strategy. Commercially oriented mindset: you measure success by outcomes, not outputs.
Preferred:
Direct experience with plasmid biology, molecular cloning, or related reagent formats (viral vectors, CRISPR tools); hands-on laboratory experience is a genuine plus.
Experience in a nonprofit, CRO, or mission-driven life science organisation where commercial goals must be balanced with broader values.
Familiarity with Addgene's portfolio, repository model, or academic distribution channels.
Experience developing or applying VOC methodologies and customer segmentation frameworks in a life science product context.
Track record of building productive working relationships with marketing, channel, and BD counterparts to drive integrated go-to-market execution.
Benefits:- At Addgene, we prioritize our people with comprehensive benefits that support both your work and your life.85% company-paid healthcare premiums including dental (extending to family members) and 100% company-paid deductible
- Life, short-term, and long-term disability insurance.22 days of PTO on top of our winter break closure and company holidays.
- A 403(b) retirement account with a company match of 4% after 2 years of employment.
- Annual professional development stipend
- Annual lifestyle stipend
- Fully paid public transportation for employees who work onsite two or more days per week.
- Onsite yoga classes & wellness reimbursement
- Pet insurance
- Annual financial planning one‐on‐ones with our plan administrator
- The Organization
Addgene is a self‐sustaining, thriving nonprofit life sciences organization that was created to help scientists share DNA‐based research materials called plasmids. Our mission is accelerate research and discovery by improving access to useful research materials and information. Since its founding in 2004, Addgene has grown and innovated in order to assist the research community by archiving and sharing useful DNA‐based research materials and resources (such as plasmids, viral vectors, and recombinant antibodies) with scientists worldwide. Broad availability of these unique research materials promotes the advancement of research in a wide variety of disciplines, including cancer, heart disease, and neurodegenerative disorders, while increasing collaboration within the scientific community. Learn more here from our President & Executive Director, Chonnettia Jones.
Life at Addgene
Addgene is a truly special place to work. We are an inclusive and welcoming group of people from many backgrounds and perspectives. We believe in flexibility, actively supporting professional development, and a strong work/life balance. We value sharing ideas and feedback with each other and the company. Learn more about Life at Addgene. We also believe it's important to make time for fun, whether it's eating popcorn at our outdoor movie night, sharing cute photos in the #pets slack channel, or sampling whiskeys at our end‐of‐year social hour. Bookworms, athletes, gamers, parents, foodies, and more will find community in Addgene's events and Slack channels.
Addgene works with a global scientific community in which the best innovations and discoveries come from diverse teams. We continuously learn from and celebrate a variety of perspectives and seek to create an environment where all people can feel heard, respected, and valued.
Addgene is an Equal Opportunity Employer and considers all applicants without regard to race, color, religion, national origin, sex, ancestry, sexual orientation, genetic information, gender identity, active military or veteran status, age, handicap, or any other characteristic protected by Federal, State or Local law.
