Lipid Nanoparticle Formulation Senior Scientist to Associate Director
newSan Diego, CA
Lipid Nanoparticle Formulation Senior Scientist to Associate Director
newSan Diego, CALead L6
Research and Development in Biotechnology (except Nanobiotechnology)Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)Research and Development in Nanotechnology
APPLY NOWCompany Description:
We are a privately held, stealth mode start-up biotechnology company developing lipid nanoparticle-based approaches to address unmet medical needs.
The role:
We are seeking an experienced hands-on and strategic Lipid Nanoparticle (LNP) Formulation Scientist to drive the design, execution, and analysis of Design of Experiments (DOE) to establish cutting-edge next-generation LNP platforms focusing on different disease areas. This role will play a critical part in developing, optimizing, and characterizing LNP systems for nucleic acid delivery in a fast-paced, collaborative research environment.
Key responsibilities:
- Design, execute, and analyze DOE-based formulation experiments to develop and optimize novel LNP formulations
- Lead formulation innovation efforts, including lipid selection, composition optimization, and novel process development
- Perform LNP screening and characterization, including size, PDI, encapsulation efficiency, stability, and performance metrics
- Lead formulation process scale-up and technology transfer as needed
- Collaborate closely with cross-functional teams (biology, analytics, chemistry, and project management) to advance programs
- Maintain thorough experimental documentation and clearly communicate results and recommendations to stakeholders
- Contribute to troubleshooting formulation challenges and continuously improve experimental workflows Professional experience and qualifications•Senior Scientist, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 3-5 years relevant experience;•Principal Scientist or Associate Director, PhD in Chemical Engineering, Bioengineering, Pharmaceutical Sciences, Chemistry, Biology, or related field with 6+ years relevant experience
- Strong hands-on experience with LNP formulations, including formulation development and optimization, process development and scaling-up
- Demonstrated expertise in DOE methodologies and statistical experimental design
- Extensive experience with LNP screening and analytical techniques
- Deep understanding of lipid-based delivery systems and formulation science principles
- Proven ability to work effectively in a team-oriented, fast-paced environment
- Strong problem-solving skills and ability to manage multiple priorities simultaneously
- Strong communication skills for presenting data and influencing technical decisions
What We Offer:
- Opportunity to work at the forefront of LNP formulation innovation
- Collaborative, science-driven culture with high impact research
- Competitive compensation and benefits package, including health, dental, vision, and life insurance
- 401(k) with company match
Matching similar jobs
Level
Lead L6
Location
San Diego, CA
Occupation
Molecular and Cellular Biologists
Industry
Research and Development in Biotechnology (except Nanobiotechnology)
Posted
8 days ago