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Senior Scientist I, Molecular Virology

generate biomedicinesSomerville, MALead L6
Overview: In this role you design and lead molecular virology research to connect early discovery with translational development. You will oversee viral vector and RNA delivery platform projects, including lentiviral systems and VLPs, and work across discovery, in vivo validation, and regulatory-ready outputs. You mentor staff, partner with computational and therapeutic experts, and drive data-driven decisions to advance clinical candidates. You will shape experiments, ensure biosafety, and communicate findings to cross-functional teams. Compensation / Benefits annual bonus equity compensation competitive benefits package
Responsibilities: Lead molecular virology research and cell culture work, including in vitro and in vivo construct design and characterization Develop and optimize high-throughput screening assays (qPCR/ddPCR, flow cytometry, Western blot, NGS) Translate complex data into decisions advancing projects toward clinical candidates Collaborate with computational scientists and therapeutic experts to evaluate viral vectors and RNA delivery platforms Maintain rigorous documentation and prepare reports, manuscripts, and regulatory content as appropriate Provide day-to-day scientific oversight, mentor junior scientists, and present findings in reviews Set research goals, track progress, and transparently report challenges and outcomes Uphold biosafety and lab compliance across activities
Key requirements: Ph.D. in Virology, Molecular Biology, Microbiology, Biochemistry, or related field 4+ years of postdoc or industry R&D experience with independent project design capabilities Hands-on experience with mammalian cell culture, viral propagation, reverse genetics, cloning, site-directed mutagenesis, and recombinant vector design Experience with qPCR, ddPCR, ELISA, flow cytometry, Western blotting, and transfection methods Experience with NGS library prep, CRISPR screening, and basic sequence/data analysis tools Demonstrated ability to apply agentic platforms and protein design tools Proficiency with ELN and LIMS Strong project management, problem-solving, and cross-disciplinary communication Strong communication and presentation skills Collaborative mindset across disciplines Ownership and accountability for projects Molecular virology techniques Mammalian cell culture Viral vector design (lentiviral systems, VLPs)
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Level

Lead L6

Location

Somerville, MA

Occupation

Molecular and Cellular Biologists

Industry

Research and Development in Biotechnology

Posted

today

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