Heath Systems Regional Scientific Director

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. The Health Systems Regional Scientific Director (HSRSD) is a therapeutic and disease expert who develops on-going professional relationships with healthcare decision makers within defined regional payer organizations (e.g., health plans, PBMs, integrated delivery systems, large GI practices, specialty pharmacy) and other key health systems in the assigned region. The HSRSD provides accurate information about Madrigal products and related disease areas, clinical science and HEOR/real-world research/evidence in a balanced and credible manner consistent with the regulatory environment and Madrigal’s ethical standards. Serves as a resource for the Global Medical Affairs (GMA) management team on strategic planning and provides mentoring for other team members. Works closely with account executives and key account managers, as well as other field medical colleagues to address the scientific needs in the region. The position reports to the Health Systems Senior Director East / West and is a remote field-based position. All incumbents are responsible for following applicable Division & Madrigal policies and procedures and are compliant with applicable policies, procedures, and regulations. Strong understanding of US regulations and compliance is required. This region will cover CO, UT, AZ and NV with the ideal location being Denver, Salt Lake City, Phoenix or Las Vegas. Key Responsibilities And Primary Activities

Clinical or scientific degree required (e.g., MD, PharmD, PhD, MS, MPH, etc.)5+ years’ experience in IDN and payer space and the ability to develop peer-to-peer relationships with key decision makers; may be gained through working on the customer side or in an industry role working with these customers. Must demonstrate a thorough knowledge of payer and IDN organizational practices Thorough knowledge of clinical medicine, the managed market environment, Pharmacoeconomics, disease management, real-world evidence generation and medical research Business and market knowledge, including quality management, formulary management and pathway development/management Excellent interpersonal communication skills, strong presentation skills, ability to work with cross functional field account teams, strong personal integrity, collaborative mindset, and strong customer focus are necessary Must possess a thorough understanding of the FDA, OIG, HIPAA and other ethical guidelines, laws and regulations relevant to the pharmaceutical industry Must be able to organize, prioritize, and work effectively in a constantly changing environment, and have demonstrated project leadership abilities Proficiency in Microsoft Office Suite, virtual communication platforms (e.g., Zoom, Teams), and related Medical Affairs Systems (e.g. Veeva Vault, CRM tools) Preferred Attributes Formal training in health economics or outcomes research Field based medical experience Liver and/or GI experience preferred, including non-viral liver disease Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $224,000 to $274,000 per year. We comply with all applicable minimum wage laws. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.