Description:
The Senior Scientist, Bioproduction & Bioprocessing is responsible for leading the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities. Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation. Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines. Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins. Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up. Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations. Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders. Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials. Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists. Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement. Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability. Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows. Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion. Provide technical insight to support long-term bioproduction strategy and organizational growth. Maintain accurate, complete, and compliant laboratory records. Ensure adherence to organizational, regulatory, and safety standards.
Requirements:
PhD in biological sciences or related field with 10 years of relevant industry experience (or Master’s degree with 13 years of experience) in bioproduction, bioprocessing, or cell line development Demonstrated expertise in stable cell line development and clone selection. Extensive hands-on experience with transient expression of antibodies or recombinant proteins. Strong foundation in mammalian cell culture and upstream protein expression. Experience with high-throughput screening, automation, or advanced analytical tools. Background in cell engineering, vector design, media/feed optimization, or bioprocess development. Prior experience in structured, milestone-driven industry or core laboratory environments. Good communication skills and ability to work collaboratively with internal team members and customers Ability to travel up to 20% MaxCyte offers a base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off. MaxCyte is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status PI66614b084a65-25448-41268244aa415a4b-8b21-40fc-a65c-70d2b25ca29a
