Sets up and performs routine and established lab procedures in support of lab goals, grant commitments, i.e., assays, cell/tissue culture, animal studies, etc. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters, and summarizes data. Assists in the maintenance of lab equipment and supplies. Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data. Presents at research laboratory meetings and contributes to writing of manuscripts. Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator. Additional duties: Under the direction of the lab manager, the Research Technologist will provide specialized histology and tissue-processing support for studies involving human brain tissue and neurodegenerative disorders. Unique responsibilities include celloidin embedding and sectioning; free-floating tissue staining; immunohistochemistry, multiplex staining, immunofluorescence, H&E, Nissl, and other specialized stains; operation of the VENTANA DISCOVERY ULTRA and automated slide-scanning platforms; coordination of tissue-processing requests with the Brain Bank; and support for RNAscope and DNA/RNA extraction workflows. Preferred experience includes working with human brain tissue, neuroanatomy, neuropathology terminology, or Brain Bank/biorepository operations. Experience with specialized histology techniques, automated staining platforms, tissue sectioning and trimming, slide preparation, and tissue or slide inventory management is also desirable. Why Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits:
Highlights Medical: Multiple plan options. Dental: Delta Dental or reimbursement account for flexible coverage. Vision: Affordable plan with national network. Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement:
Competitive retirement package to secure your future. Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. Equal Opportunity All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. Requires bachelor's degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. BS/BA in biological sciences, biomedical sciences, neuroscience, laboratory sciences, histotechnology, biomedical research preferred. Must exhibit a solid understanding of lab techniques, equipment, and safety. Must have the ability to organize and carry out laboratory techniques independently and in a team setting. Experience with basic data analysis is required, as well as demonstrated writing skills.
Additional Qualifications
Required:
Experience working in a research, clinical, pathology, histology, biorepository, or wet-lab environment.
Ability to precisely and carefully follow SOPs, written protocols, safety requirements, and set quality guidelines under the direction of the lab manager.
Strong attention to detail and organizational skills for specimen handling, labeling, staining, inventory, and laboratory documentation.
Ability to work safely with human tissue specimens, laboratory reagents, and shared research equipment following appropriate training.
Strong communication skills and ability to work effectively as part of a collaborative research team.
Qualifications
Preferred:
Experience with free-floating tissue staining, immunohistochemistry, multiplex staining, special stains, or related histology techniques.
Experience with the VENTANA DISCOVERY ULTRA or a similar automated staining platform.
Experience with RNAscope, or willingness to learn and perform RNAscope workflows.
Experience with or willingness to learn DNA and RNA extraction techniques.
Familiarity with human brain tissue, neuroanatomy, neuropathology terminology, or Brain Bank/biorepository operations.
Experience with tissue sectioning, trimming, slide mounting, coverslipping, labeling, and maintenance of tissue or slide inventories.
Note:
Visa sponsorship is not available for this position. Must be U.S. citizen, permanent resident, refugee or asylee. Full time
Posting Date: 2026-10-09
