Lead Architect, Microsoft 365 & Copilot Platforms

Vertex Pharmaceuticals Incorporated is seeking a Principal Engineer for Microsoft 365 and Copilot Platforms. This role blends hands-on work with strong technical leadership to deliver secure, governed Modern Work and AI capabilities across Teams, SharePoint, OneDrive, and Exchange. You will lead Copilot-related initiatives, coordinate across teams, and drive automation while maintaining governance and security controls in a regulated enterprise environment.