Senior Research Associate Next-Generation Sequencing (NGS) needs 3 5 years of bench experience falls dire • End-to-End Library Prep: Lead RNA-seq, bulk, amplicon, and highly specialized single-cell (scRNA-seq) and single-nucleus (snRNA-seq) sequencing workflows. • Target Identification: Design and execute molecular and cell biology experiments to identify and validate novel drug targets. • Assay Optimization: Support assay design, optimization, validation, and complex data quality control (QC). • Troubleshooting: Diagnose and resolve complex technical data anomalies to keep drug discovery projects moving forward. • Collaborative Reporting: Translate complex experimental results into clear oral presentations and written documentation. • Education & Experience: B.S. and/or M.S. in biological or biochemical sciences with 3 5 years of hands-on laboratory research experience. • Molecular Biology Mastery: Proven expertise in nucleic acid extraction, purification, quantification, qPCR, and NGS library prep/QC. • Advanced Sequencing Background: Deep understanding of NGS technologies and data QC (preferably Illumina), with direct experience in bulk RNA-seq and amplicon-seq. • Single-Cell Expertise: Direct experience with scRNA-seq and snRNA-seq library preparation is required. You must be familiar with multiple platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences). • Operational Excellence: Experience documenting experiments in electronic notebook software, alongside exceptional organizational and time-management skills. Preferred Extras (A Plus, But Not Required) • Familiarity with CRISPR-based gene editing and high-throughput screening. • Experience operating lab automation equipment (Mantis, Integra systems, liquid handlers, SPTLabtech Firefly, Tecan, etc.).
