LCMS Scientist Seeking a LCMS Scientist to be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.
Duties:
Responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.
Perform high throughput quantitative in vivo and in vitro LC-MS/MS analysis, troubleshooting and problem solving of small molecule and peptides from various bio-matrices.
Operate, perform routine maintenance, and hands-on troubleshooting of AB Sciex LC-MS/MS systems.
Maintain excellent documentation of all work including LIMS, test methods, and protocols.
Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.
Qualifications:- Bachelors, Masters, or Ph.D. in Biochemistry, Analytical Chemistry, or related discipline typically with 8+ (BS), 6+ (MS), or 0+ (PhD) years of relevant academia/pharmaceutical experience.
- Proven method development experience using various extraction, chromatographic and analytical methodologies.
- Proven experience with quantitative bioanalysis of small molecules.
- Proven experience operating and troubleshooting Agilent HPLCs, Leap/CTC PAL autosamplers and AB Sciex Mass Spectrometers
- Detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.Strong communication, interpersonal, and presentation skills.
Work experience in regulated bioanalysis and/or CRO Facility settings is a plus.
Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
Learns fast, grasps the "essence" and can change course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Quantitative LC-MS experience
Proven record of independent work
Understanding of small molecule analysis in biomatrix
Understanding of peptides and proteins in biomatrix is a plus
Reverse phase method development is a plus
First Shift, Mon-Fri, 8am - 5pm (possibility of earlier than 8am depending on job tasks)
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first of the month following at least 1 calendar year after employment begins.
Synectics is an equal opportunity employer.
