Director, Advertising Promotion (Remote-Eligible)

Job Title: Director, Advertising Promotion (Remote-Eligible) Job Location: Boston, MA Job Location Type: Remote Job Contract Type: Full-time Job Seniority Level:

General Summary: The Advertising Promotion Director is responsible for providing strategic and tactical regulatory direction and support for the management of review and approval of product, pipeline and disease state communications for Vertex product(s) and/or Development program(s), including promotional and non-promotional materials and communications from varied stakeholders including Commercial, Medical, Corporate Communications and Public Affairs. This role works collaboratively and cross-functionally in the development and implementation of processes that support meeting business objectives and meet regulatory requirements. Key Duties and

Responsibilities: Provides direction and expertise as a Regulatory expert on region/country regulations and requirements governing product promotion and related communications, including pipeline and disease state communications Serves as Regulatory reviewer on Communications Review Committee (CRC) and Medical Review Committee (MRC), and as Global Regulatory Affairs Advertising and Promotion (GRA-AP) representative on program and other cross-functional teams Functions as Chair of CRC for assigned product(s) and therapeutic area(s), leading discussions between Regulatory, Legal, Medical, Commercial and other stakeholders to reach consensus CRC decisions As Regulatory Reviewer, assesses the regulatory context and provide regulatory interpretations of applicable guidance and/or regulations or regulatory precedents, including requirements related to submission of material to Health Authority (HA) and interact with HA, as applicable Enhances collaboration across a matrixed organization while developing and maintaining constructive relationships with CRC stakeholders Provides direction and input for development products reflective of promotional considerations Provides direction to ensure that changes in product labeling are carried into promotional materials in accordance with company procedures and regulatory requirements Provides leadership and direction for cross-functional efforts to develop and update procedures and guidelines related to CRC processes Monitors and interprets advertising and promotion regulations and guidelines to support successful and compliant marketing of Vertex products; assesses impact on Vertex business and stakeholders Leads training sessions as needed with stakeholders Knowledge and Skills: High level of applied knowledge of applicable Health Authority codes, laws, regulations, guidance, and industry standards related to advertising and promotional communications about prescription drugs, devices (if applicable), and investigational treatments In-depth understanding of clinical study design and statistical analyses in assessment of promotional claims Familiarity with labeling regulations and global promotional review Excellent interpersonal skills with ability to lead, interact with, influence, resolve conflict and drive consensus among individuals from a variety of cultures and disciplines Demonstrates the ability to effectively adopt and leverage emerging technologies, including AI-driven tools, and maintains a continuous learning mindset to strengthen regulatory strategy, decision-making, and operational efficiency. Proactively remains up to date on advances with technology, AI, automation, competitive intelligence and changes in the regulatory environment. A solutions-driven mindset, with skills in complex reasoning and risk management assessments Excellent communication skills (oral and written), project management and presentation skills Pharmaceutical industry and regulatory ad/promo experience, including managing launch campaigns and interacting with Health Authorities Education and Experience: Bachelor's degree in relevant/scientific discipline or a related field Typically requires 10 years of experience or the equivalent combination of education and experience At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $188,000 - $282,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefitsto meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1.Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Polic

Location: United States