Radiochemist The University of Texas MD Anderson Cancer Center is a leading institution dedicated to eliminating cancer through exceptional patient care, groundbreaking research, comprehensive education, and prevention programs. The Radiochemist role supports these efforts by advancing the development, validation, and quality control of innovative radiopharmaceuticals used in research and clinical applications. Within the Nuclear Medicine Research Department, the Radiochemist contributes technical expertise in radiochemistry, analytical testing, and radiopharmaceutical development. The Radiochemist works closely with scientific staff, engineers, and laboratory personnel to develop novel tracers, optimize processes, support regulatory compliance, and advance research initiatives. The Radiochemist plays a critical role in ensuring quality, safety, and scientific excellence throughout the product development lifecycle at UT MD Anderson. The ideal candidate for this role will possess educational preparation and experience in radiochemistry, analytical chemistry, radiopharmaceutical development, or a related scientific discipline. Candidates should demonstrate expertise in analytical techniques, method development, quality control operations, scientific communication, and radiation safety practices. Licenses and certifications were not provided; therefore, candidates meeting the minimum required qualifications will be considered.
Responsibilities:- Quality Control Operations
- Perform quality control procedures in accordance with established Standard Operating Procedures (SOPs) using radio-HPLC, GC, TLC, and related analytical techniques
- Validate and implement analytical methods independently or collaboratively as required
- Draft documentation, SOPs, and quality documents supporting technical transfer of radiotracers for future clinical trials
- Troubleshoot analytical methods and resolve technical issues affecting testing processes
- Interpret analytical data and maintain analytical results with appropriate backup recordkeeping
- Report equipment malfunctions and perform minor repairs when possible
- Maintain equipment service, calibration, and quality records
- Maintain accurate laboratory records and serve as a subject matter expert during root cause investigations
- Research & Development
- Provide input into strategic planning efforts for new product lines
- Develop and optimize radiolabeling procedures and analytical methods as assigned by the Principal Investigator
- Contribute to planning and development of new radiopharmaceuticals and analytical procedures
- Evaluate technical feasibility of new products in collaboration with scientific staff
- Collaborate with engineers and technical experts on target design, scale-up activities, and operational handoff
- Provide scientific recommendations, innovative ideas, and technical input to the Principal Investigator
- Develop and validate synthesis processes for novel PET, SPECT, and radiotherapeutic tracers
- Characterize radiolabeled products, troubleshoot processes, and interpret experimental data
- Optimize formulations and radiolabeling processes to improve product performance
- Develop analytical methods for characterization of radiolabeled products
- Technical Expertise & Laboratory Safety
- Utilize analytical techniques including HPLC-MS, HPLC, iTLC, and HPGe for product analysis and characterization
- Troubleshoot radiochemistry challenges using both manual and automated approaches
- Develop strategies with laboratory personnel supporting in-vitro and in-vivo studies involving radiotracers
- Ensure compliance with radiation safety, contamination control, and radioactive waste management requirements
- Verify functionality and calibration of radiation safety equipment within the laboratory
- Support radiation safety control management efforts across laboratory workspaces
- Funding Support & Scientific Communication
- Assist in preparing scientific components of grant applications
- Author and edit reports, presentations, and other documents summarizing scientific findings and collected data
- Maintain effective communication of scientific activities with internal and external stakeholders
- Publish scientific results in peer-reviewed journals
- Present scientific findings at scientific meetings and professional conferences
- Other Duties As AssignedEDUCATION
Required: Bachelor's Degree Chemistry, Biochemistry or related field.
Preferred: Master's Degree Chemistry, Biochemistry or related field. WORK EXPERIENCE
Required:
3 years Experience in manufacturing and/or quality control of PET radiopharmaceuticalsLICENSES AND CERTIFICATIONS
Preferred:
Authorized user listed in Radioactive Materials (RAM) License as per Nuclear Regulatory Commission (NRC). Upon HireThe University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
