Opportunity for Secondment to AskBioWe're pleased to share an exciting secondment opportunity at AskBio. This role is available for a time period to be determined by leadership at both Bayer and AskBio. While most assignments range from one to two years, the exact duration will be based on business needs and mutual agreement. This secondment offers a unique chance to broaden your experience, expand your knowledge, and contribute meaningfully to AskBio's mission: to advance gene therapy and change the lives of patients around the world. If you're interested in exploring this opportunity, we encourage you to: Speak with your direct manager to discuss your interest and alignment with your development goals. Apply directly using the link provided in the posting. We look forward to seeing how our colleagues continue to grow and make an impact across the Bayer-AskBio partnership.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission:
Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.
Our values:
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what's right in every situation. Make clear commitments and follow through.
Position Summary:
The Senior Research Associate, Immunology is one of the key laboratory members who will have an opportunity to contribute to the understanding of AAV Immunogenicity by performing analyses on clinical study samples using immunological assays in support of our gene therapy programs. The Senior Research Associate will contribute to activities in the lab to drive assay development and validation, real-time immune assessments of clinical studies, as well as clinical sample coordination and management. This is an excellent opportunity for a candidate who is looking to build his/her experience in Cell Biology and Immunology lab skills as they transition to a larger role in developing, validating and performing more complex assays associated with gene therapy to advance clinical programs. Reporting to the Senior Director of Immunology, this position is a full-time on-site role located in Philadelphia, PA.
Job Responsibilities:- Performance of complex assays without supervision
- Perform assay development of new clinical assays which may include the optimization, qualification, validation, and troubleshooting of new analytical methods
- Perform data analysis and interpret the results accurately
- Preparation of validation reports and summaries
- Coordinate with Clinical team and/or Immunology lab manager for sample receiving and testing
- Participate in team and clinical program meetings as needed to report results, discuss data and address program needs
- Build and maintain a compliant GxP lab environment and adhere to GLP/GcLP guidelines
- Author standard operating procedures (SOPs) for new assay protocols and use of new laboratory equipment
- Maintain a laboratory notebook or binder with worksheets recording details of performed experiments according to good documentation practices
- Train and mentor Research Associates, contractors, and junior members of the laboratory
Minimum Requirements:- Bachelor's degree in a related field with 5+ years of experience; or Master's degree in a related field with 2+ years of experience; or High School Diploma with 9+ years of experience
- Advanced lab skills in cell biology, cell culture, immunology, reagent preparation, and adherence to biosafety and chemical use guidelines
- Familiarity with handling and working with human clinical lab samples
- Familiarity with GCP/GLP/GxP lab standards and practices
- Flexible schedule to accommodate real-time and urgent sample analysis; May include weekend, holiday and after-hours availability
- Advanced office skills using a PC and working with MS office tools (Word, Excel and PowerPoint)
- Must be self-motivated, organized, capable of working independently as well as a team contributor
- Strong oral and written communication skills, particularly in writing technical documents such as SOPs, assay validation plans, reports and clinical sample testing plans and reports
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally
- Ability to work independently with minimal supervision under direct/remote management but also work collaboratively with a broader team and across functional departments
- Preferred Education, Experience and Skills
- Experience in immunoassays such as ELISA, ELISPOT/FluoroSpot, neutralizing antibody, MSD, cytokine release and flow cytometry
- Previous experience with handling clinical lab samples and blood processing workflow
- Experience with LIMS systems (e.g. LabVantage)
- Familiarity with statistical analysis
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job-related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at talent@askbio.com.
