Principal Scientist, Oligonucleotide Design & Chemistry

Genentech's Therapeutic Modalities and Technologies group in Protein Sciences is seeking a Principal Scientist (Group Leader) to lead the design and synthesis of novel oligonucleotide modalities for drug discovery. You will guide a multidisciplinary team, mentor scientists, and shape portfolio strategy in a dynamic, on-site South San Francisco setting. The role emphasizes technical leadership, collaboration with biology teams, and rapid decision-making to accelerate research outcomes.