Principal Scientist, Bioinformatics & AI for Discovery

Legend Biotech US is seeking a Principal Scientist, Bioinformatics in Somerset, NJ to lead AI-driven discovery and binder design for CAR-T therapies. You will develop generative AI models, apply geometric deep learning, and work within a multidisciplinary R&D team to identify novel tumor targets and optimize protein binders for improved efficacy and safety. The role emphasizes advanced computational biology, multi-omics integration, and structure-based design, with collaboration across protein